Piedmont Reproductive Endocrinology Group

For more than a decade, Piedmont Reproductive Endocrinology Group (PREG) has helped thousands of patients throughout the Carolinas to become parents. Committed to providing the highest caliber fertility care, coupled with a stress-free, affordable and efficient approach, Piedmont Reproductive Fertility Group has become one of the most respected fertility practices in the region, with an earned reputation for consistently excellent success rates and patient satisfaction scores.

After serving in various clinical leadership positions in the Divisions of Reproductive Endocrinology at both East Carolina University School of Medicine and Greenville Hospital Systems in Greenville, Dr. John E. Nichols, Jr., double Board Certified in OB GYN and Reproductive Endocrinology and Infertility (REI), realized his long-held goal of opening his own private fertility practice serving the Upstate area.

Piedmont Reproductive Endocrinology Group opened its doors in 2003 and began helping to create families for Carolinians suffering with infertility. Dr. Nichols later recruited in 2007 double Board Certified OB GYN/REI, Dr. John F. Payne, who had been serving as the Chief of Reproductive Endocrinology and Infertility at Walter Reed Army Medical Center. More recently, Dr. James F. Holman, also Board Certified in OB GYN and REI joined the PREG team in 2013 and sees patients in our Asheville location.

Drs. Nichols, Payne and Holman are supported by a skilled and compassionate team of infertility staff including embryologists and laboratory technicians, infertility nurse practitioners and registered nurses, each of whom has years of experience in the infertility field, and knowledgeable administrative patient and financial counselors. All PREG team members are focused on helping to create a personalized plan of care for each individual patient with one goal in mind — that each patient realizes their goal of having a healthy pregnancy and a take-home baby.

PREG has three strategically located offices which are equipped with the latest, cutting edge technology. The fully accredited, state-of-the-art IVF Center, surgical suite and Endocrine and Andrology laboratories are located in Greenville, SC. To further ensure access for patients in northern SC and western NC, the Spartanburg and Ashville offices are both well-appointed and conveniently located. In response to patient demand, PREG has opened a new Columbia location to better serve the growing needs of South Carolinians who are trying to build their families.

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Piedmont Reproductive Endocrinology Group offers the entire range of infertility testing, diagnosis and treatment services for men, women and couples. Conventional treatments with on-site hysterosalpingogram (HSG) and office hysteroscopy, minimally invasive laparoscopy including robotic assisted procedures, out-patient tubal reversals at our fully accredited surgical suite as well as advanced reproductive technologies including IUI, IVF, ICSI, Embryo biopsy for pre-implantation screening and genetic testing, Egg and Embryo Freezing and Third Party Reproduction Services (Donor Egg, Donor Embryo, and Gestational Carriers) are available. PREG offers treatment programs for Endometriosis, fibroids, Recurrent Pregnancy Loss, Fertility Preservation/Egg Freezing (banking), Onco-Fertility, Polycystic Ovarian Syndrome (PCOS), as well as LGBT Parenting. Specialized services for those in need of genetic evaluations, PGD/PGS are also available.

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